All About Stem Cells
For life to begin an egg cell is fertilized by a sperm, after that it divides and become an embryo. Inside every embryo are stem cells that can become cell types of each bodily organ. Scientists and medical researchers obtain embryos using two ways. Some by way of in vitro fertilization. Using this process, the sperm and eggs are fertilized using a culture dish in a laboratory. The eggs would develop into embryos and would be implanted back in the female. But during this process a lot of embryos are created more than what is needed to be implanted. The extra embryos that are no longer needed in the impregnation process are frozen. By the consent of the couples these are donated for stem cell research.
Three main types of Stem Cell:
- Embryonic Stem Cells
- Adult Stem Cells
- Induced Pluripotent Stem Cells
The second method that scientists obtain embryos is through cloning. It involves merging a cell from the patient who needs the stem cell therapy with a donor egg. Doctors remove the nucleus from the egg and replaces it with the nucleus coming from the patient’s cell. The egg is stimulated and divides either by electricity or using chemical process, the embryo that comes out of this will carry the genetic material of the patient. The method reduces the risk that the human body will reject the stem cells once implanted. Embryos contain eight cells, then after five more days the embryo develops into a ball of cells and turns into a blastocyst. Each blastocyst contains 100 cells in total together with stem cells. Stem cells stored inside are now pluripotent and could already develop into any cell type as needed.
Medical researchers would then remove these stem cells from the blastocyst and culture them in a Petri dish inside the laboratory. These stem cells would then divide several times and scientists can now transfer them into other culture dishes. Millions of stem cells can be produced using this process and if by chance these cells continue to grow without differentiating, then scientists would now have a stem cell line.
Expectant mothers are being encouraged to store their umbilical cord blood after giving birth through an umbilical cord banking. This is because the umbilical cord contains stem cells coming from the fetus. These stem cells can be harvested and grown into culture. Fetal stem cells coming from the Umbilical cord blood are multipotent. The umbilical cord fluid is overflowing with stem cells. It can be used to treat cancer, anemia and other immune system disorders making it very valuable.
Mothers can decide to keep the umbilical cord with the help of a cord blood bank. The doctor clamps the umbilical cord and inserts a needle and collects at least 40 milliliters of blood from the chord. This blood is then sealed in a bag and sent to the laboratory or the cord blood bank for testing and storage. This process is painless and only takes a few minutes.
Embryonic Stem Cell
An embryonic stem cell is classified as pluripotent which means that they can grow into three germ layers: the ectoderm, endoderm and the mesoderm. This type of stem cell can develop into more than 200 cell types of the adult body, if they are instructed to do so. Embryonic stem cells can replicate forever. It can regenerate making it a useful tool for medical science and regenerative medicine. Embryonic stem cells can reproduce in a limitless way making it ideal for clinical trials.
Embryonic stem cells are grown inside laboratories through the process known as cell culture. These stem cells are transferred cells from preimplantation stage and then transferred into a plastic laboratory culture dish that contains nutrient broth also known as culture medium. Once transferred the cells begin to divide and spread over the culture dish. During the early stages of Stem Cell Research experiments, they coat the culture dish with mouse embryonic skin cells that have been treated so it doesn’t divide. The mouse cells are needed to create a sticky surface, so that the cells will attach. The feeder cells are then supplied to provide nutrients in the culture dish. Today doctors no longer use this method and devised other ways to grow embryonic stem cells. Doctors no longer use mouse feeder cells to remove the possibility of contaminating the human’s cells with mouse cells.
The process of growing stem cells in the culture dish is very hard, a lot of the embryonic stem cells don’t survive. But once they do due to ideal life conditions, it divides and begins to fill the dish. They are then removed gently and plated into different fresh culture dishes. This re-plating occurs many times for several months and is called sub-culturing. Once the cell line has been established, the original cells will now yield millions of embryonic stem cells. This process can last several months without differentiating and the stem cells that appear from this method is genetically normal and become an embryonic stem cell line. Successful batches of the culture dish are then frozen and shipped to laboratories for further culture, research and experimentation.
Scientists want to create a rich source of stem cells for clinical testing. Once a stem cell line has been established it becomes immortal. A researcher who is using this stem cell line will no longer go through rigorous processes of obtaining stem cells every now and then. By growing them in a stem cell laboratory they can harvest and freeze indefinite numbers of stem cells for storage and distribution. Established stem cell lines that are grown into the lab offer a range of opportunities to engineer them either for transplantation or to cure various diseases. In the past, scientists need to overcome numerous attempts to prepare patients so that their immune system will not reject the transplant. But as science progresses, we are now discovering a way to modify human stem cell lines in laboratories making gene therapy less complex and less prone to immune rejection. Once we reach the ultimate way of doing this, we can easily replace damaged genes, add new genes to stem cells and give it more characteristics to help eliminate many diseases in the future.
Stem cell research is the most promising branch in medicine because it is the study of the ultimate blocks of life that comprise the human body. If we would learn how to generate new cells and transplant them into the body without fail or rejection, then we can reverse the damage. The blood stem cells are used to provide a source of healthy blood cells for people suffering from various blood conditions including cancer patients who have lost a good quality of healthy blood cells during treatment.
The study of stem cells has gone a long way. Stem cell clinics are now offering different solutions to various human illnesses and diseases. Stem cell therapy is offering a new generation of treatment- and it banks on the principle of being able to replace dysfunctional stem cells in the body to make the body renew its vigor and help extend human lifespan.
Scientists currently believe that the ability to understand the ability of stem cells will lead us to key answers we have been hoping for. The goal is to unlock the full potential and power of stem cells so we can understand how to treat serious medical conditions using stem cells. Before stem cells could be of use to us, we must first understand the genetic and molecular processes that are happening within. Scientists are digging down the rabbit hole and going back to understanding molecular and genetic signals, so we know how to properly regular cell division and each specialization.
Currently, the best defined and most extensively used stem cell treatment is Hematopoietic or blood stem cell transplantation. Bone marrow transplantation is used to treat blood and immune system disorders and can rebuild the blood system. In some cases, issues like skin, bone and eye injuries can be treated by grafting or implanting issues. The effectiveness of the method would rely on the quality of the stem cells implanted and the way the body of the patient will receive it. These procedures are now widely accepted as safe by medical doctors. But other applications of stem cell therapy are still under clinical trials and in the experimental stage.
While hematopoietic stem cells taken from the bone marrow is considered the most potent kind of stem cell treatment. Doctors now understand that there are also other stem cells freely circulating in the bloodstream. Scientists eventually learned to harvest these cells and now transplant them directly into a donor. Peripheral blood stem cell transplant or PBSCT is becoming a common procedure in clinics because it is less invasive and doesn’t require removal of marrow from the hip bone.
Benefits of Stem Cell Therapy
Every day our human body undergoes daily stress and we lose healthy cells, once these stem cells are depleted and unable to replenish in time, our body suffers from inflammation and mutations and our bodily organs decline over time. Without proper care and timely medical intervention most of our cells eventually die and this is when disease progression and diseases happen. Stem cell therapy is the only treatment that is focused on curing aging. The goal is to strengthen the stem cells of the body, to replenish it, so that our energy and zest for life is prolonged.
Stem cells has the unique ability to regenerate and offer powerful anti-aging effects. It is highly regarded and deemed valuable by the medical community because it is now proven effective to strengthen organs, tissues and cells that were damaged by stress, injury or exposure to toxins and pollutants.
One of the primaries uses of stem cell therapy is for orthopedic care. After scientists discovered the impact of bone marrow stem cells, they began to use it for solving bone repair, cartilage replacement and soft tissue repair. Stem cells is now used for removal of chronic bodily pains, it is recommended for patients who suffer inflammation and recurring injuries. Feeling Good at Any Age the One Stop Rejuvenation Center is focused on providing advanced stem cell clinic procedures for clients and undergoes thorough and careful testing before recommending to patients.
Clinic Patients who have experienced having their knees injected with stem cells claim that it is almost no pain! One female patient of FGAAA who suffered from osteoarthritis and in severe pain is now pain free after getting stem cell injections. She stated that she only experienced a small swelling and pain due to the needle pricks, but her knees feel fantastic, after years of suffering arthritis she is now feeling stronger and more confident to face life. FGAAA stem cell anti-aging therapy is an outpatient procedure with no post procedure downtime. Feeling Good at Any Age the One-Stop Rejuvenation Clinic follow strict FDA guidelines and procedures when conducting therapies.